Diclofenac Diethylamine + Combination ROll on(Gel)

Indications -
Anti-inflammatory
Approved Name -
Diclofenac Diethylamine + Combination Roll On (Gel)
Gel (Roll on) Presentation:

Each Roll on contains:
Diclofenac Diethylamine IP 1.16 % w/w
equivalent to Diclofenac Sodium IP 1.0 % w/w
Linseed Oil BP 3.0 % w/w
Methyl Salicylate IP 10.0% w/w
Menthol IP 0.5 % w/w
Benzyl Alcohol IP 1% w/w

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DESCRIPTION

This combination is used to relieve the joint pain, stiffness, swelling in arthritis. diclofenac is phenyl acetic acid derivative and non -steroidal anti -inflammatory drug Diclofenac inhibit cox -1 and cox-2 enzyme and prevents the synthesis of prostaglandins.
Linseed oil is known by name flaxseed oil. It is rich in ALA which helps reduction of joint of inflammation. Methyl salicylate: it is the methyl ester of the salicylic acid. It is topically used to provide relief against joint pain caused strains, sprains and arthritis. Methyl salicylate is known as counter irritant. Menthol provides cooling sensation and act as counter irritant. It acts as the activator of the transient receptor potential melastatin compound. Benzyl alcohol has local anaesthetic activity and relieves the superficial skin pain and also has preservative action.

Indications
  • Rheumatoid arthritis
  • Sprain & strain
Mechanism

Diclofenac - diclofenac is phenyl acetic acid derivative and non -steroidal anti -inflammatory drug Diclofenac inhibit cox -1 and cox-2 enzyme and prevents the synthesis of prostaglandins.
Methyl salicylate - it works by causing the skin to feel cool and warm this helps in reducing pain of joints, muscles and tendons
Menthol - it works by imparting the cooling effect by activating nociceptors and desensitize that receptors and reduces pain.
Linseed oil - flaxseed oil is the source of the polyunsaturated fatty acids. It contains alpha- linolenic acid that decreases the inflammation so therefore it is useful in the rheumatoid arthritis and other inflammatory diseases.

Contraindications

contraindicated in people with known allergy.contraindicated in people with known allergy.contraindicated in people with increase chances of bleeding

Side Effects
  • itching
  • dryness
  • blistering of the skin
  • allergic reactions
  • increased swelling
Warnings
  • Be careful not to get the medication in your eyes, nose, mouth, or on any open wounds or broken skin.
  • Keep away from Eye
  • Do not swallow
How to use
  • Gently clean and dry the area where you intend to apply the medication. This helps to ensure better absorption.
  • Gently roll the applicator over the affected area to apply a thin layer of the medication. Make sure to cover the area evenly. Do not apply too much pressure; a light roll is usually sufficient.
  • Allow the medication to dry on its own; do not rub it into the skin.
  • After applying the medication, wash your hands thoroughly unless you are treating your hands.

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