Saar Biotech

Saar Biotech Pvt. Ltd. is a distinguished WHO-GMP certifiedpharmaceutical manufacturing company in Baddi, Chandigarh, renowned for its dedication to quality and innovation. Since 2005, we have been at the forefront of the industry, operating from our state-of-the-art facility in Baddi, with a central office in Chandigarh.

Specializing in third-party contract manufacturing, we partner with over 1700 clients to deliver a wide range of pharmaceutical products, including Suspensions,Syrups, Ointments, Roll Ons, covering various therapeutic segments. Ourextensive experience and advanced technology make us a trusted choice for companies seeking reliable manufacturing solutions.

At Saar Biotech, quality and service are our top priorities. Our stringent quality standards ensure each product meets regulatory requirements and exceeds customer expectations. We are committed to providing the best service and product quality in the industry.

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DESCRIPTION

Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAIDs). NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins (PGs). PGs contribute to inflammation and pain signalling. Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation from a variety of causes.

Indications

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  Acute Migraine
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  Gouty Arthritis
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  Pain
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  Post Operative Pain
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  Rheumatoid Arthritis
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  Acute Musculoskeletal injury
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  Mild to moderate joint pain

Mechanism

Diclofenac reduces inflammation and by extension reduces nociceptive pain and combats fever. It also increases the risk of developing a gastrointestinal ulcer by inhibiting the production of protective mucus in the stomach. Diclofenac inhibits cyclooxygenase-1 and -2, the enzymes responsible for production of prostaglandin (PG) G2 which is the precursor to other PGs. These molecules have broad activity in pain and inflammation and the inhibition of their production is the common mechanism linking each effect of diclofenac. PGI2 and PGE2 contribute to acute inflammation via their IP and EP2 receptors. PGI2 and PGE2 modulate T-helper cell activation and differentiation through IP, EP2, and EP4 receptors which is believed to be an important activity in the pathology of arthritic conditions. By limiting the production of these PGs at the site of injury, NSAIDs can reduce inflammation.

Interactions

The risk or severity of bleeding and hemorrhage can be increased when Diclofenac is combined with warfarin and 4-hydroxycoumarin. The risk or severity of hypertension can be increased when Diclofenac is combined with 1-benzylimidazole and 4-Methoxyamphetamine.

Side Effects

The product is possible safe for most adults. There is no disadvantage associated with the product if taken under the recommended usage however itching, increased sweating, dryness, scaling, or peeling may occur in some patients.

Warnings

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  Not to apply on cuts and wounds
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  Keep away from Eye
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  Do not swallow

How to use

Apply a drop of gel onto the affected area and rub onto the skin. The amount of gel required will vary depending on the size of the area to be treated. Wash hands after use.