Composition:
Sodium Chloride IP 0.9 % w/v
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Isotonic nasal spray is a non-medicated saline solution with a salt concentration similar to that of your body fluids (0.9% NaCl). It gently cleans, hydrates, and soothes dry or congested nasal passages.
Sodium chloride — major electrolytes of the fluid compartment outside of cells (i.e., extracellular) — work together to control extracellular volume and blood pressure. Disturbances in sodium concentrations in the extracellular fluid are associated with disorders of water balance.
Sodium the major cation of the extracellular fluid, functions primarily in the control of water distribution, fluid balance, and osmotic pressure of body fluids. Sodium is also associated with chloride and bicarbonate in the regulation of the acid-base equilibrium of body fluid. Chloride, the major extracellular anion, closely follows the metabolism of sodium, and changes in the acid-base balance of the body are reflected by changes in the chloride concentration.
Sodium chloride:
Absorption: of sodium in the small intestine plays an important role in the absorption of chloride, amino acids, glucose, and water. Chloride, in the form of hydrochloric acid (HCl), is also an important component of gastric juice, which aids the digestion and absorption of many nutrients. The volume of distribution is 0.64 L/kg
Elimination: Substantially excreted by the kidneys.
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